Search on: RECEPTORS, SIGMA 
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Descriptor English:   Receptors, sigma 
Descriptor Spanish:   Receptores sigma 
Descriptor Portuguese:   Receptores sigma 
Synonyms English:   sigma Receptors
Opioid Receptors, sigma
Receptors, sigma Opioid
Receptors, Opioid, sigma  
Tree Number:   D12.776.543.750.100.620.775
D12.776.543.750.720.600.610.775
D12.776.543.750.750.555.610.775
Definition English:   A class of cell surface receptors recognized by its pharmacological profile. Sigma receptors were originally considered to be opioid receptors because they bind certain synthetic opioids. However they also interact with a variety of other psychoactive drugs, and their endogenous ligand is not known (although they can react to certain endogenous steroids). Sigma receptors are found in the immune, endocrine, and nervous systems, and in some peripheral tissues. 
Indexing Annotation English:   opioid receptors; DF: RECEPT SIGMA
History Note English:   93; was SIGMA RECEPTOR (NM) 1981-92 
Allowable Qualifiers English:  
administration & dosage agonists
antagonists & inhibitors analysis
biosynthesis blood
chemistry classification
drug effects deficiency
genetics history
immunology isolation & purification
metabolism physiology
radiation effects therapeutic use
ultrastructure  
Record Number:   30546 
Unique Identifier:   D017480 

Occurrence in VHL:
 

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